Snuggling a baby may help their genes and future health


Snuggling a baby may help their genes and future health

Close, physical contact – or the lack of it - at an early age may lead to lasting changes to the genes, suggest researchers.

The team at the University of British Columbia in Vancouver, Canada, showed that babies receiving less physical contact during times of emotional distress developed a significantly altered epigenome compared with children receiving lots of contact. Their epigenomes were also under-developed by comparison.

'In children, we think slower epigenetic ageing could reflect less favourable developmental progress,' said Professor Michael Kobor, senior author on the study published in Development and Psychopathology.

The epigenome refers to the semi-permanent chemical changes or 'marks' added on to human DNA that can act as on/off switches for genes.

The team asked the parents of 94 five-week-old babies to keep daily diaries recording physical contact with their child and their infants' behaviours, such as sleeping and crying, during the duration of the study. DNA swabs were taken from the children four to five years later.

The researchers looked at a specific epigenetic change called DNA methylation. They found consistent differences in the methylation pattern between children who received a lot of contact, to those receiving less contact, at five DNA sites. Of these, two sites were within genes: one involved in metabolism and the other in the immune system.

The researchers were concerned by an additional finding: as people age their epigenomes alter according to a predictable pattern as genes are turned on and off during development. But the children who showed higher levels of emotional distress and received less physical affection had a younger 'epigenetic age' than they should have had.

'We plan to follow up on whether the "biological immaturity" we saw in these children carries broad implications for their health, especially their psychological development,' said lead author Dr Sarah Moore. 'If further research confirms this initial finding, it will underscore the importance of providing physical contact, especially for distressed infants.'

Article source: 4th December 2017